Each year, friends and fellow artists are selected to write short tributes to the honorees.
Lauper says, "Look at this guy. You want to see living proof of talent, perseverance, tenacity, resilience, dedication to craft? When he couldn’t get in the front door, the side door or the window, he found a whole other route. And now—especially since his historic Emmy win for Lead Actor in a Drama Series last fall—the whole world has found him, and that makes me so happy."
Winfrey wrote, "There's no one else like him. In the entertainment business and in life. He's a true visionary. A trailblazer. In 2005, I saw my first Tyler Perry play. I knew then he was special. I watched the audience laugh, cry and delight in seeing themselves reflected in the story onstage."
See the full list of honorees here.
The issue also includes a memorial to Justice Ruth Bader Ginsburg, including the tribute that fellow Justice Antonin Scalia wrote when she was on the TIME 100 in 2015.